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Names
X
Name
Species
Main
PML
Homo sapiens, Mus musculus
True
TRIM19
False
Keywords
X
APB, apoptosis, cancer, DNA repair, histone deacetylase complex, leukaemia, leukaemia_associated translocation, telomere, nucleolus, PML bodies, RBCC, SUMO, zinc finger B_box, ER, alt, telomere maintenance
Location
X
Location
Species
15q22
Homo sapiens
9
Mus musculus
Subcellular Localisation
X
Stage
Description
Details
Links
Interphase
PML/ND10 bodies
relatively immobile
PubMed:11238464
Interphase
nucleolar
upon proteosome inhibition by MG132, or phosphorylation by ATR
PubMed:15195100
PubMed Central:11158586
Interphase
repair foci
PubMed:12642865
Interphase
ALT-associated PML body
enlarged PML body in ALT cells
PubMed:15075340
pachytene
XY body
PubMed:15349788
Interphase
clastosome
PubMed:16818720
Interphase
endoplasmic reticulum
pubmed:21030605
Protein Sequence
X
MwPredict
PIPredict
MwActual
PIActual
AANo
Links
97.5
5.88
882
Entrez Protein:P29590
OMIM:102578
Uniprot:P29590
90
5.38
808
PubMed: 96116962
Entrez Nucleotide: NM_008884
Annotation
X
Start
End
Domain
Description
1
633
full length
57
91
RING finger
124
166
B-Box Zn finger
1
808
full length
31
65
RING finger
98
140
B-Box Zn finger
Biological Process
X
GO ID
Term
Links
GO:0006342
chromatin silencing
PubMed:11259576
GO:0006325
establishment and/or maintenance of chromatin architecture
PubMed:17173041
GO:0006918
induction of apoptosis by p53
PubMed:14992722
PubMed:12907596
pubmed:21030605
GO:0000122
negative regulation of transcription from Pol II promoter
GO:0032205
regulation of telomere maintenance
pubmed:1956747
pubmed:25908860
Molecular Function
X
GO ID
Term
Links
Other Function
X
Function
Links
Expression
X
Experiment
Detail
Links
Related Genes
X
Name
Species
Links
History
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